Abstract: Filling mining is one of the key links in the green mining technology system of coal mines, in view of the transportation technology of the gangue-fly ash based filling slurry during the filling process, parameters such as different mass concentrations, fly ash content, curing temperature and time were set. The rheological tests of the gangue-fly ash based filling slurry under the temperature-time coupling effect were carried out to explore the influence of various parameters on the rheological properties of the slurry. Through orthogonal range analysis, the influence weight of temperature and standing time on the yield stress of the slurry was analyzed, and the rheology under the temperature-time coupling effect parametric regression model was established. The test results show that the mass concentration has a significant effect on the fluidity of the slurry. With the increase of the mass concentration, the linear correlation between the shear stress of the slurry and the shear rate decreases. When the mass concentration is 78%, it has both good fluidity and stability; The increase of the fly ash content will increase the shear stress and the degree of shear thickening. When the amount of fly ash is 85%, the yield stress of the slurry is the largest, followed by the amount of fly ash of 75%, and the amount of fly ash 65% is the smallest; High temperature accelerates the hydration reaction rate of the slurry and enhances the pozzolanic reactivity of fly ash. The curing temperature at 50 ℃ increased by 44.5% and 37.5% respectively compared with 20 ℃ and 35 ℃ when the fly ash was kept for 120 minutes; The setting time has a stronger influence on the yield stress of the slurry than that of temperature. When the fly ash content is 75%, the yield stress of the slurry after standing for 120 minutes at a temperature of 20 ℃ increases by 133.7% compared with that of standing for 0 min; Under different temperature conditions, the yield stress of the slurry increases linearly with standing time, and the degree of fitting is above 0.9. Finally, the yield stress evolution model of the slurry under the temperature-time coupling effect is established. By comparing the calculation results of the theoretical model with the test results, the average error is about 5%, and the fitting effect is good, which can provide a reference for the calculation of the pipeline transportation resistance of the filling pipeline in the coal mine.