Abstract: With the continuous development, processing and utilization of coal resources in our province, the existence of typical harmful elements in coal is bound to have a negative impact on the efficient and clean utilization of coal resources. Based on the mass data analysis of typical hazardous elements in coal of Huainan coalfield, taking the main coal seams (No.13-1, No.11-2, No.8, No.6, No.4 and No.1) as the research objects, the occurrence characteristics and geological genesis of typical hazardous elements were comprehensively analyzed by the means of ICP-MS, AFS, stepwise chemical extraction and cluster analysis. The results were as follows: ① Typical hazardous elements Cr, Co, Se and Pb in coal of Huainan coalfield are “lightly enriched”, Hg is “highly enriched” and other elements are in “normal range”; ② The high value area of As element content in Huainan coalfield was mainly located in the west of coalfield; the high value region of Hg element was located in the east of coalfield, followed by the west; the remaining eight elements (Cr, Mn, Co, Ni, Se, Cd, Sb and Pb) were all higher in coal of Panji mining area of Huainan coalfield (especially near Pansan coal mine). The late magmatic hydrothermal process in Panji-Zhuji region may be the main reason for the relative enrichment of hazardous elements such as Cr, Mn, Co, Ni, Se, Cd, Sb and Pb. ③ There were many ion-exchange States in the occurrence state of Hg, and the inorganic components brought by magmatic hydrothermal action may have little influence on the enrichment degree of Hg element. The magmatic hydrothermal intrusion in the late diagenesis period had no obvious influence on As, and the low content of As in coal may be related to the low content of As in coal-forming plants.