Abstract: Large open-pit coal mines often encounter fault structures with different development scope and degree within the mining boundary. In order to optimize and determine the relevant parameters of the working slope passing through the fault in the open-pit coal mine, the change of the working slope passing through the fault mode and the length of the working line when the relative position between the working line and the fault strike is different is analyzed, the principle of coal resource recovery in the fault affected area is determined, and the influencing factors of the production stripping ratio change in the process of working slope advancing when the working line intersects the fault strike are expounded. According to the basic principle of open-pit mining, the engineering model of the strike arrangement of the intersecting faults of the working slope is established, the composition of the working line is discussed, and the calculation method of the working line length is given. The three-dimensional space rectangular coordinate system with the working line layout direction and the working side advancing direction as the axis is constructed, the section stripping volume and raw coal volume of each engineering model are calculated, and the functional relationship between the working line length, the angle between the working line and the fault strike, the working side advancing distance and the production stripping ratio is determined. The change rule of production stripping ratio is analyzed by means of control variables. The results show that the initial production stripping ratio is positively related to the length of the fault descending wall working line when the stripping working line is orthogonal to the fault strike; When the strike of the oblique fault of the working wall is advancing, the initial production stripping ratio is negatively related to the length of the working line of the fault riser and the angle between the working line and the fault strike. The smaller the angle between the working line and the fault strike, the more intense the change of the production stripping ratio. This paper presents the optimization principle of the parameters of the working slope passing through the fault in the open-pit coal mine, and puts forward the method of determining the parameters by using the computer program to judge circularly. Taking Shengli West No. 2 Coal Mine as the engineering background, the above optimization principles and determination methods are applied and studied. The results show that when the angle between the working line and the fault strike is 70 ° and the length of the initial footwall mining working line is 1700 m, the production stripping ratio of the working side is less than the economic and reasonable stripping ratio in the process of advancing in the F13 fault area, the length of the working line always meets the minimum working line length requirements for equipment operation, running and deployment, and the east side slope expansion is the minimum.