Abstract: In order to study the influence of coal body structure and macrolithotype of coal in high rank coal on coal body adsorption and desorption, The data of coal petrography, coal quality, isothermal adsorption and desorption of 79 coal rock samples from 55 coal-bed methane wells in No.3 Coal Seam in the south of Qinshui Basin were collected, and the change laws in the Langmuir volume (V_L), Langmuir pressure (P_L), desorption rate of coal samples with the same macrolithotype of coal, different coal body structures and the same coal body structure, different macrolithotype of coal of coal samples, were discussed in the influential mechanisms of coal body structure and macrolithotype of coal on coal body adsorption and desorption. The results show that the average V_L of coal samples in the study area is 37.00 m³/t, of which 86.61% is distributed in 33.00—41.00 m³/t, and the average P_L is 2.82 MPa, of which 82.28% is distributed in 2.30~3.30 MPa. The adsorption and desorption capacities of fractured coal are better than those of primary structure coal and the difference of pore connectivity caused by structural destruction is the fundamental reason for the difference of desorption and adsorption characteristics between primary structural coal and fractured coal; The development degree of pores and fissures of primary structure coal is different from that of fractured coal. The methane emission effect of fractured coal is better than that of primary structure coal because of more developed pores. The decreasing rule of surface free energy of coal for methane adsorption is the mylonitic coal > granulitic coal > fractured coal > primary structure coal, which reflects the difference of methane adsorption capacity of coal with different coal structure; the adsorption and desorption capabilities of the three types of macro coals are bright coal > semibright coal > semidull coal. On the one hand, the specific surface area of coal decreases roughly in the order of bright coal, semibright coal, and semidull coal, which reflects the difference in adsorption sites on the surface of the coal matrix. On the other hand, it is caused by the difference of vitrinite and inertinite content between vitrain and durain. The purpose of this study is to further reveal the occurrence and production mechanism of CBM in high-rank coal reservoirs, and to provide a basis for the optimization of CBM favorable areas and target horizons.