Abstract: In view of high maintenance cost of trucks in the production and transportation of open-pit mine, a combination of periodic preventive maintenance and minor repairs was adopted for truck. Considering the change rule of failure rate after periodic preventive maintenance of open-pit mine truck, based on age-reduction model, periodical preventive maintenance strategy of open-pit mine truck was studied. According to the characteristics of the weibull distribution of open-pit mine truck failure rate function, introducing age-reduction factor to reflect change in the failure rate of open-pit mine truck after each cycle of periodic preventive maintenance, established the failure rate function of open-pit mine truck after each cycle of periodic preventive maintenance. Based on the failure rate function of open-pit mine truck, total preventive maintenance cost model including periodic preventive maintenance costs and minor repair costs of open-pit mine truck was established, and solution algorithm was designed to obtain optimal periodic preventive maintenance strategy for open-pit mine truck. The results show that: when operating time of open-pit mine truck was determined, preventive maintenance cost first decreases and then increases with the increase in the number of preventive maintenance, and first becomes smaller and then larger as the preventive maintenance cycle becomes longer; As the operating time increases , the number of optimal preventive maintenance increase slower; The optimized periodic preventive maintenance strategy for open-pit trucks requires less cost than the common maintenance strategy, and the difference becomes larger as the operating time becomes  longer. Constructing failure rate function of open-pit mine truck based on the age-reduction model, and to study the periodic preventive maintenance strategies of trucks with different operating hours, which can provide effective solutions for preventive maintenance and management of mining equipment.