Abstract: In order to prevent and control the mine rock burst of the irregular face clamped with the fault, a mechanics model of the fault-induced rock burst was established and was applied to analyze the cause of the rock burst. An expression formula of the lateral support pressure of the irregular face was obtained and applied to analyze the causes of the rock burst. The numerical simulation and theory were applied to analyze the in-situ stress, structure stress and mining stress affected to the induction mechanism of the rock burst. The rock burst causes of the coupling face with the fault and irregular double factors as well as the rock burst behavior features were obtained. The rock burst coupling prevention principle and technical system of the fault clamped irregular face was provided. According to the geology and mining condition of the certain seam, based on the chamber, the water injection and blasting boreholes as the principal measures were applied to form the completed prevention and control technology of the continued defect mass. A site practices were conducted on the completed prevention technology of with the defect prevention and control of the local prevention technology with the fault zone and irregular zone as well as the irregular coal pillar zone as the principal prevention measures. The affectivity of the defect prevention and control technology system was approved.