Abstract: In order to accurately predict a mine water inflow of Zhaoxian Mine and to correctly guide the safety production of the mine,based on the analysis of the mine hydrogeological features,the "big well method",water collection channel method and analogy method were applied to the calculation of the mine water inflow and to predict the mine water inflow of the mine roof strata. Static reserves were calculated. The calculation method and equation of the mine water inflow were provided when the separated strata water were evenly discharged. The analogy method was applied to determine the disaster water inflow. The study results showed that a water discharging project before the mining operation of the coal mining face could effectively discharge the aquifer in the roof. With no consideration of the water in the separation strata,the normal water inflow of No. 1307 coal mining face was 110.33 m3/h and the max water inflow was 584.12 m3/h. The water inflow of the separated strata evenly discharged could be considered as 249 m3/h. The disaster water inflow of the separated strata water could be considered as 1 100 m3/h and the study results could improve the reliability and accuracy of the prediction to the mine water prevention and control.