Abstract: Due to the gas pressure, gas content and ground stress were all large in deep coal mining, the methods were proposed to decrease the gas pressure an d gas content through protective seam mining and gas drainage, and increased coal seam permeability by hydraulic measures. The field test in deep coal mine, such as Xinzhuangzi Coal Mine, Panyi Mine, Pingdingshan Mining Area and Niuerzhuang Coal Mine showed that, after adopting these measures, the gas content was decrease d obviously, the gas drainage value and coal seam permeability coefficient were increased significantly.Therefore, the comprehensive gas control measures based on pr otective seam mining, gas drainage and hydraulic measures could obviously reduce gas disaster and ensure safety in deep coal mining.