Abstract: In order to prevent and contral the coal spontaneous combustion in the goaf caused by the slow advancing speed, coal left in the goaf, serious ventilatio n leakage and others during the initial mining period of No.3301 fully mechanized top coal caving mining face in Yangcheng Mine, in combination with the mine actual C onditions, the comprehensive control measures to speed up the coal mining face advancing speed, to adjust ventilation value, to reduce the ventilation leakage, to injec t glues, to inject inert gas and to spray the inhibitor were provided.The results showed that after the comprehensive control measures applied, the CO volume fraction in the air returning flow of No.3301 fully mechanized top coal caving mining face was reduced from 501.25x10-6 to 17x10-6.Thus a safety mining during the initial mining period could be ensured.