Abstract: In order to analyze the influence factors of the seam gas content in Zhaiyadi Mine, a method combined with the site measurement, the lab measurement and the theoretical derivation was applied to analyze the roof and floor lithology of the seam, the boundary of lithology, the adsorption constant of the coal to the gas an d other factors.The analysis obtained a relationship between the gas content of No.6 seam and No.9 seam and the thickness of mudstone in the roof.The analysis confir med that the gas content of No.6 seam in Zhaiyadi Mine was higher than the gas content of No.9 seam and was related to the mudstone thickness of the roof above sea m, the boundary of the lithology and the regional geology evolution.The secondary factors affected to the gas content of No.6 seam would be the coal adsorption consta nt and the coal porosity mainly.