Abstract: In order to have the connectivity of the coalbed methane reservoir in the Block of Qinshui Basin and the preferential seepage direction between the well s, No. SH- 39, No. SH- 47, No. SH- 48 and No. SH- 49 wells as the test well group were applied to the interference test wells of the coalbed methane well. Precision dir ect- reading pressure gauges were set down in the observation wells and a water injection with certain volume was made into the active well. With the analysis and expl anation conducted on the pressure variations at the bottom of the active well, the connectivity of the reservoir and the preferential seepage direction between the wells could be obtained.The results showed that No. SH- 39 well was connected with No. SH- 48 well and No. SH- 4 well, the strata connectivity between the observation well - -No. SH- 48 well and the active well- -No. SH- 9 well was a lttle better than the connectivity between the observation well- -No. SH- 49 well and the active well- -No. S H- 39 well. Therefore, the preferential seepage direction of the coalbed methane reservoir in the regional measured was in a north- east direction and could provide the basis to the well network layout of the regional coalbed methane and well network optimization.