Abstract: In order to further improve the efficiency of the mine water disaster regional control technology in the deep operation mine and to reduce the danger from floor water inrush, with the Hanxing Mining Area as an example, the paper summarized and analyzed the mine water disaster regional control experiences and the majo r problems existed in the present deep operation mines. The paper provided the study status and difficulties, including the karst development law, mine water disaster C ontrol mode, directional well design and construction technique optimization, controlled grouting technique, comprehensive identification technology of the hydrological i nformation and the establishment method of the mine water disaster control system in the deep operation mine and other key technologies.And the paper provided the t endency of the each technology study and development.