Abstract: In order to prevent coal reservoir damage and underground gas drainage equipment failures caused by coal fines generation,taking the coalbed methane( C BM) development in Hancheng as an example, based on the anisotropy of coal reservoir features and characteristics of stages in coalbed methane production,the mechanic al mechanism,characteristics and rules of coal fines generation were analyzed. The comprehensive analysis of prevention and control measures for coal fines was conducte d through geological prediction and prevention,reservoir reconstruction remission,production control,technology and equipment management. The results showed that the mechanical mechanisms of coal fines generation included reservoir pressure fluctuation and engineering reconstruction disturbance.There were dual features of difference s in space and stages in time duration for coal fines characteristics of yield,composition,particle size and morphology.The application of comprehensive prevention and cont rol measures,such as identification of tectonic coal development and complexity of coal seam texture by logging data,inhibition of rock and fluid interactions in inorganic mi nerals,capture and immobilization of coal fines by nanoparticles,rational management of production intensity and stabillization of reservoir pressure change,forewarning of C oal fines aggregation degree by monitoring indicator diagram,well washing and equipment optimization,can effectively mitigate the damage of coal fines.