Abstract: There were several irregular coal pillars in No.3303 coal mining face during the initial mining period in Tangkou Mine.Those irregular coal pillar zones wo uld cause unfavorable influences to the surrounding rock stress condition and distribution of the coal mining face.There was a possibility of the mine pressure bumping occurred in the coal mining face.In order to prevent the mine pressure bumping occurred during the initial mining period of the coal mining face, a numerical simulation study was conducted on the stress conditions during the initial mining period of the coal mining face and the surrounding rock stress conditions and mine pressure bum ping danger of the coal mining face with three stages of the inclined pushing forward, revolving mining and horizontal pushing forward were analyzed.There were six mi ne pressure bumping dangerous zones divided.During the mining process, the stress monitoring and measuring was conducted on the dangerous zone.Once the danger found, a drilling blasting and pressure releasing measures would be applied to eliminate the mine pressure bumping danger.The practices showed that with the division of the mine pressure bumping dangerous zones and analysis on the danger, the related prevention measures provided could effectively prevent and control the mine pr essure bumping occurred in the coal mining face.