Abstract: According to the hydrogen sulfide control problem of the coal mining face under the multi structural geological condition in a coal mine, a site probe monitoring and the miner’s portable detector monitoring were applied to real time monitor the variation of the hydrogen sulfide concentration. With the coal samples selected from the coal mining face, the hydrogen sulfide content was conducted at the mine site and the indoor lab. An isoline software was applied to draw the deposition isoline map of the hydrogen sulfide content in a coal mine and the distribution law of the hydrogen sulfide content in the coal mining face was studied. At the same time, the stage control plan was adopted. Thus,before the coal cutting operation at the gateway of the coal mining face, long borehole alkaline liquid pre-injection and the alkaline liquid injections in the drilling wall of the coal wall in the coal mining face were applied to eliminate the hydrogen sulfide in the seam of the coal mining face. During the coal cutting, alkaline liquid spraying from the coal shearer as well as the air curtain to guide the ventilation after the coal cutting and the powered support water curtain absorption measures were applied to control the hydrogen sulfide. The comprehensive control measures were conducted before the coal cutting, during the cutting and after the coal cutting. The control results showed that the comprehensive control measures could reduce the concentration of the hydrogen sulfide in a deferent degree and the overall control effect was obvious. Thus the coal miners in the coal mining face and the safety and high efficient coal mining of the coal mining face could be ensured.