Abstract: In order to classify the mine with different types of water disaster and make corresponding measures for water prevention and control, mine inflow value, water inrush value and unit inflow value of the main aquifer were selected to be clustering index.The fuzzy clustering analysis method based on MATLAB was applied.C ombined with hydrogeology condition analysis of 11 mines, the optimal classification number is 4.The first kind of min water disaster were surface water, burnt rock wat er and wind oxidized zone water, prevention and control measure was keep the coal (rock) pillars.The second was coal roof water, advanced detection and preliminary drained should be taken.The third was structural water, probing structure should be needed.The last was coal roof water and mine inflow was large .Probing water abun dance of aquifer on coal roof was suggested.The results showed that the fuzzy clustering analysis method based on Matlab not only conform to complex and fuzzy char acteristics of the mine water disaster, but also has the characteristics of quickly and accurate.