Abstract: Due to the single index of CO could not effectively predict the seam spontaneous combustion in Dafosi Mine, with the simulation on a site real air leakag e and thermal storage condition, the paper studied the variation law of the multi parameters prediction indexes gas from the coal spontaneous combustion in Dafosi Min e with the coal temperature rising. According to the experiment results, a multi parameters prediction indexes system was determined mainly with φ( CO) /φ ( CO2), GI aham index and Oφ ( CO) /Oφ ( 02) . The results showed that when φ ( CO) /φ ( CO2) index below 0.1、0.1 ~0.2、over 0.2 and when the Graham index was below 3、 3 ~6、over 6, were individually corresponded to an oxidization stage of the spontaneous combustion, an oxidization acceleration stage of the spontaneous combustion and a serious oxidization stage of the spontaneous combustion for Dafosi Mine coal sample.