Abstract: According to the features of the multi layer inclined rock strata roadway drilled through by No. 12061 floor gas drainage roadway in Guocun Mine, the paper analyzed the asymmetrical deformation law and causes of the mine roadway after the previous symmetrical support technology applied. The FLAC3D simulation software was applied to the comparison and analysis on the surrounding stress filed, displacement field and plastic zone scope before and after the support of the typical drilling through layers roadway. A initial shotcreting + bolt/steel mesh + steel bar ladder + anchor + second shotcreting + grouting combined support was provided as well as the bolt/steel mesh/anchor and the grouting enhanced support combined asymmetrical support method applied to the soft and weak rock strata and the above support methods were applied to the mine site. The result showed that in comparison with the previous symmetrical support technology, after the application of the asymmetrical support technology, the deformation of the mine roadway was in stable within above 40 days, the convergence between the roof and floor of the mine roadway and the convergence between the two sidewalls of the mine road were all reduced over 70%, the asymmetrical deformation of the mine roadway was effectively controlled which could provide certain references to the support technology of the complicated difficult mine roadway.