Abstract: Based on'first escape,fter hedge' 'concept for persons in distress underground mines after coal mine disasters,in order to resolve the problem that effective protection time of the currently existing self-rescuer was not long enough and difficult to escape the disaster because of shorter escaping distance when persons in distress once wore and used self-rescuer,developed a long time self-rescuer of isolated and compressed oxygen,which had 120 minutes protection time,quality 4.5 kg and three kin ds of supply oxygenation for quantitative oxygen,manual and automatic oxygen supply.With humanoid breath test platform,it was validated by experiments that three key te chnical parameters for oxygen concentration,carbon dioxide concentration and intake air temperature in 120 minutes,the results showed that oxygen concentration was not lower than 25%、carbon dioxide concentration less than 2% and intake air temperature not more than 50 °C in protection time ,three indicators met the requirements of the standard for self-rescuer of isolated and compressed oxygen.