Abstract: Take the goaf of No.2103 fully mechanized top coal caving mining face in Weijiadi Mine as a study object, a study was conducted on the gas drainage wi th high level boreholes along the roof strike in goaf and the grout spraying fire prevention and control.The results showed that the high level boreholes along roof strike could replace the roof gateway for the gas drainage in goaf.Meanwhile, when an indication of spontaneous combustion occurred in goaf, the high level boreholes could be applied to be a grout sparing borehole.Before the high level borehole applied for the grout spraying, the max volume fraction of CO in goaf released to the air retunin g gateway was 0.003 6% . After the grout spraying completed, the volume fraction of CO was reduced below 0.000 5% and the fire prevention and control in goaf was re alized.The integrated application of gas drainage and the grout spraying fire prevention and control with the high level borehole along the strike conducted in the sponta neous combustion seam would have the good applied prospect.