Abstract: In order to prove the mine gas geological law to well guide prevention and control of mine gas disaster, taking Panyi Mine of Huainan Coalfield as a stud y object, the mine gas geological unit of Panyi Mine was divided. The study results showed that the coal measure strata of Panyi Mine in Huainan Coalfield were recons tructed mainly by the tectonic movements during the Late Triassic and Late Jurassic- Early Cretaceous and tectonic features of different period occurred in the internal of the strata. Based on major fault F4 and fault F5 in the mine as a boundary, three gas geological units were divided. A study was conducted on the gas geological law of the three gas geological units. The structure coal distribution law, gas content and gas pressure, gas weathering zone depth and gas dynamics phenomenon in each gas geological unit were revealed and could provide guidance to the prevention and control of the mine gas disaster.