Abstract: In order to get good performance of lignin dispersant in coal water slurry, taking alkali lignin as raw materials, the coal water slurry dispersant was prepa red by using the high pressure homogenization- H202coupling activation technique and sulfonated polycondensation modification method. The optimum processing con dition was determined by orthogonal method, pH value was 11, the amount of H2O2 was 8% of alkali lignin mass, the pressure of high pressure homogenization was 50 MPa, the amount of Na2SO3was 25% of alkali lignin, the amount of HCHO was 10% of alkali lignin, the sulfonated polycondensation temperature was 80 °C, the sulfona ted polycondensation time was 4 h. The slurry ability of coal water slurry tests showed the high pressure homogenization- H2O2coupling activation optimum technique C ould improve the slurry density with 1. 21% compared with alkali lignin dispersant without high pressure homogenization activation.