Abstract: In order to research the response rule of acoustic emission about coal and rock with different fissures and heterogeneity in the loading process, original permeability and acoustic emission parameters in the loading process about the coal samples with different fissures and heterogeneity in Sihe Coal Mine were tested by the RMT-150B rock mechanics test system and acoustic emission system. The results showed that acoustic emission energy increased quickly to maximum in the late s tage of plastic deformation or in the early stage of elastic deformation when the fractures of coal samples were uniform, then the energy decreased slightly and maintai ned at a level. Acoustic emission energy was high at the beginning of the elastic deformation, then the energy increased to the maximum, finally the energy maintained at a certain value when the fractures of coal samples were non-uniform and developed. The experimental results had a good prediction on the deformation of coal and r ock in the process of coal mining.